Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668748 | 0.87 | CCNE2 (0.57) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7533542 | 0.86 | GSK3B (0.50) | GSK3BQPCTCCNE2CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL7533156 | 0.84 | MAPT (0.47) | GSK3BQPCTCCNE2CDK4CCND1 | |
| SCHEMBL7976420 | 0.84 | GSK3B (0.67) | GSK3BCCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7532464 | 0.83 | CCNE2 (0.44) | GSK3BCCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7524287 | 0.83 | CDK2 (0.44) | GSK3BQPCTCCNE2CDK4CCND1 | |
| SCHEMBL7508119 | 0.82 | CCNE2 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL7990839 | 0.82 | CDK2 (0.43) | GSK3BQPCTCCNE2CDK4CCND1 | |
| SCHEMBL7526686 | 0.82 | GSK3B (0.44) | GSK3BQPCTCCNE2CDK4CCND1 | |
| SCHEMBL7497956 | 0.82 | GSK3B (0.57) | GSK3BQPCTCCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | claimed |
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |