Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | FABP7 | O15540 | 10/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 8/20 | 0.42 |
| ▸ | FABP3 | P05413 | 6/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821368 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APOLBEDNRA | |
| SCHEMBL30311957 | 0.78 | POLB (0.62) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4439254 | 0.77 | PPARG (0.53) | ALDH1A1MEN1KMT2APOLBPPARG | |
| SCHEMBL1196033 | 0.70 | PPARG (0.50) | ALDH1A1PPARGGAAFABP7FABP5 | |
| SCHEMBL15590565 | 0.68 | POLB (0.70) | ALDH1A1POLBEDNRAPPARGGAA | |
| SCHEMBL20614651 | 0.68 | POLB (0.70) | ALDH1A1POLBEDNRAPPARGGAA | |
| SCHEMBL12694388 | 0.68 | POLB (0.64) | ALDH1A1POLBEDNRAPPARGGAA | |
| SCHEMBL21120223 | 0.68 | POLB (0.70) | ALDH1A1POLBEDNRAPPARGGAA | |
| SCHEMBL20598122 | 0.68 | POLB (0.70) | ALDH1A1POLBEDNRAPPARGGAA | |
| SCHEMBL8643008 | 0.68 | POLB (0.64) | ALDH1A1POLBEDNRAGAAFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274699-B1 | ENDCAPPING WITH A ISOBENZOFURAN COMPOUND | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2001-08-14 | — | — | US | disclosed |