SCHEMBL7977018

SCHEMBL7977018

COC1(C#N)C=CC=CC1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28695973 0.79 CYP11B1 (0.31) CYP11B1
SCHEMBL18493643 0.72 CYP11B1 (0.34) CYP11B1
SCHEMBL8418758 0.69 CYP11B1 (0.31) CYP11B1
SCHEMBL20663200 0.67
SCHEMBL28519720 0.67
SCHEMBL27889290 0.66
SCHEMBL28189606 0.66
SCHEMBL8046570 0.65 CYP2A6 (0.34)
SCHEMBL14046939 0.64
SCHEMBL18903867 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed