SCHEMBL8046570

SCHEMBL8046570

CCc1ccc(C#CC2(OC)C=CC=CC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.34
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6734125 0.65 CYP2A6 (0.58) CYP2A6ACACB
SCHEMBL5050178 0.65 CYP2A6 (0.64) CYP2A6ACACB
SCHEMBL8228398 0.65 CYP2A6 (0.64) CYP2A6ACACB
SCHEMBL28695973 0.65 CYP11B1 (0.31)
SCHEMBL7977018 0.65 CYP11B1 (0.39)
SCHEMBL28486650 0.62 TSHR (0.32)
SCHEMBL4799978 0.61 APP (0.59) CYP2A6ACACB
SCHEMBL9856109 0.61 CYP2A6 (0.40) CYP2A6ACACB
SCHEMBL19629593 0.60 CYP2A6 (0.47) CYP2A6ACACB
SCHEMBL9855155 0.60 CYP2A6 (0.39) CYP2A6ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-B1 Liquid crystalline compound, liquid crystal composition containing the same, and display device CHISSO CORP (JP) 2000-06-14 EP disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed