Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657411 | 0.83 | S1PR1 (0.61) | RAB9ANPC1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL18040200 | 0.81 | NOTUM (0.70) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL17595755 | 0.81 | NOTUM (1.00) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL28869608 | 0.81 | NOTUM (0.68) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL12477652 | 0.81 | NOTUM (0.69) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL2089284 | 0.81 | NOTUM (0.68) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL655414 | 0.81 | NOTUM (0.68) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL91541 | 0.81 | NOTUM (0.68) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| SCHEMBL7598545 | 0.79 | S1PR1 (0.81) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5656477 | 0.79 | NOTUM (0.67) | NOTUMRAB9ANPC1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |