Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27701334 | 0.73 | SLC6A3 (0.38) | SLC6A3TDP1SLC6A2 | |
| SCHEMBL27698946 | 0.73 | SLC6A3 (0.40) | SLC6A3TDP1SLC6A2SLC6A4DHFR | |
| SCHEMBL19946897 | 0.72 | SLC6A3 (0.40) | SLC6A3TDP1SLC6A2SLC6A4DHFR | |
| SCHEMBL19946898 | 0.72 | SLC6A3 (0.40) | SLC6A3TDP1SLC6A2SLC6A4DHFR | |
| SCHEMBL8447006 | 0.72 | SLC6A3 (0.38) | SLC6A3TDP1SLC6A2SLC6A4DHFR | |
| SCHEMBL25020759 | 0.71 | — | — | |
| SCHEMBL6109208 | 0.71 | — | — | |
| SCHEMBL5997655 | 0.71 | — | — | |
| SCHEMBL4829491 | 0.71 | — | — | |
| SCHEMBL27916092 | 0.70 | SLC6A3 (0.43) | SLC6A3TDP1SLC6A2SLC6A4DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |