Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158442 | 0.84 | TSHR (0.65) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL13821653 | 0.83 | TSHR (0.60) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL2687790 | 0.83 | TSHR (0.56) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL78979 | 0.82 | — | — | |
| SCHEMBL14590513 | 0.81 | SMN1; SMN2 (0.64) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL415383 | 0.81 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL7977181 | 0.81 | TSHR (0.58) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL2746390 | 0.80 | RECQL (0.57) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| SCHEMBL20405434 | 0.80 | ALDH1A1 (0.61) | TSHRSMN1; SMN2RECQLLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1669235 | 0.80 | CA12 (0.52) | TSHRSMN1; SMN2LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |