Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 10/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401740 | 0.84 | SRD5A1 (0.58) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8023777 | 0.80 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL9306767 | 0.80 | SRD5A1 (0.47) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8895974 | 0.79 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL8021062 | 0.79 | SRD5A2 (0.51) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8006823 | 0.79 | SRD5A1 (0.59) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL8006820 | 0.79 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL4266160 | 0.79 | SRD5A1 (0.66) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL4266165 | 0.79 | SRD5A1 (0.66) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 | |
| SCHEMBL24503471 | 0.78 | SRD5A1 (0.74) | SRD5A1SRD5A2LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035553-A1 | PROCESS FOR PREPARING ANDROSTENONE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-22 | — | — | WO | disclosed |
| EP-0298652-B1 | Dehydrogenation process and intermediates | MERCK & CO INC (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5187278-A | Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-aza-5α-androstan-3-one steroids | MERCK & CO., INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5116983-A | Azasteroids as intermediates | MERCK & CO., INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0473226-A2 | Trialkysilyl trifluoromethanesulfonate mediated functionalization of 4-aza-5alpha-androstan-3-one steroids | MERCK & CO. INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5091534-A | Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-AZA-5α-androstan-3-one steroids | MERCK & CO., INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5084574-A | Reacting a 3-oxo-4-azasteroid with a silyating agent and quinone to form a double bond at the #1 ring position | MERCK & CO., INC. (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0298652-A2 | Dehydrogenation process and intermediates | MERCK & CO. INC. (US) | 1989-01-11 | — | — | EP | disclosed |