Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023777 | 0.83 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL8006823 | 0.82 | SRD5A1 (0.59) | SRD5A1SRD5A2 | |
| SCHEMBL8006820 | 0.82 | SRD5A1 (0.56) | SRD5A1SRD5A2 | |
| SCHEMBL8021062 | 0.82 | SRD5A2 (0.51) | SRD5A1SRD5A2 | |
| SCHEMBL8023756 | 0.81 | SRD5A1 (0.52) | SRD5A1SRD5A2 | |
| SCHEMBL8007037 | 0.81 | SRD5A1 (0.62) | SRD5A1SRD5A2 | |
| SCHEMBL8016931 | 0.81 | SRD5A1 (0.53) | SRD5A1SRD5A2 | |
| SCHEMBL8023100 | 0.81 | SRD5A1 (0.57) | SRD5A1SRD5A2 | |
| SCHEMBL797724 | 0.79 | SRD5A1 (0.55) | SRD5A1SRD5A2 | |
| SCHEMBL5803950 | 0.79 | SRD5A1 (0.59) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693810-A | ENZYME INHIBITORS OF TESTOSTERONE-5ALPHA-REDUCTASE TO PREVENT OR LESSEN SYMPTOMS OF DIHYDROTESTOSTERONE-RELATED HYPERANDROGENIC CONDITIONS, E.G. PROSTATE PROBLEMS, SKIN DISORDERS | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | claimed |
| EP-0663924-A4 | 17-g(b)-CARBOXANILIDES OF 4-AZA-5-g(a)-ANDROSTAN-3-ONES AS 5-g(a)-REDUCTASE INHIBITORS. | MERCK & CO INC (US) | 1995-10-04 | — | — | EP | claimed |
| EP-0663924-A1 | 17$g(b)-CARBOXANILIDES OF 4-AZA-5$g(a)-ANDROSTAN-3-ONES AS 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1995-07-26 | — | — | EP | claimed |
| WO-1994007861-A1 | 17β-CARBOXANILIDES OF 4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1994-04-14 | — | — | WO | claimed |