Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1883178 | 0.91 | CYP11B2 (0.72) | CYP11B2CYP11B1 | |
| SCHEMBL1874639 | 0.80 | CYP11B1 (0.74) | CYP11B2CYP11B1 | |
| SCHEMBL1874620 | 0.79 | CYP11B1 (0.76) | CYP11B2CYP11B1 | |
| SCHEMBL1882137 | 0.78 | CYP11B1 (0.76) | CYP11B2CYP11B1 | |
| SCHEMBL1876932 | 0.77 | CYP11B1 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL15850901 | 0.77 | CYP11B1 (0.64) | CYP11B2CYP11B1 | |
| SCHEMBL1875838 | 0.77 | CYP11B2 (0.60) | CYP11B2CYP11B1 | |
| SCHEMBL1877532 | 0.77 | CYP11B1 (0.63) | CYP11B2CYP11B1 | |
| SCHEMBL1882608 | 0.77 | CYP11B1 (0.57) | CYP11B2CYP11B1 | |
| SCHEMBL6912080 | 0.77 | CYP11B1 (0.57) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135651-A1 | 6-PYRIDIN-3-YL-3,4-DIHYDRO-1H-QUINOLIN-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HUMAN ALDOSTERONE SYNTHASE CYP11B2 | UNIVERSITÄT SAARLANDES (DE) | 2009-11-12 | — | — | WO | disclosed |