Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977662 | 1.00 | L3MBTL1 (0.39) | L3MBTL1MAPTNPSR1MAPK1OPRK1 | |
| SCHEMBL8116917 | 0.94 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL8116916 | 0.94 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1ALDH1A1GAA | |
| SCHEMBL7976341 | 0.93 | L3MBTL1 (0.37) | L3MBTL1MAPTNPSR1MAPK1OPRK1 | |
| SCHEMBL7976343 | 0.93 | L3MBTL1 (0.37) | L3MBTL1MAPTNPSR1MAPK1OPRK1 | |
| SCHEMBL7982118 | 0.91 | L3MBTL1 (0.36) | L3MBTL1MAPT | |
| SCHEMBL7982117 | 0.91 | L3MBTL1 (0.36) | L3MBTL1MAPT | |
| SCHEMBL7690629 | 0.91 | L3MBTL1 (0.37) | L3MBTL1MAPT | |
| SCHEMBL7690627 | 0.91 | L3MBTL1 (0.37) | L3MBTL1MAPT | |
| SCHEMBL7684765 | 0.91 | MAPT (0.37) | L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |