Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995223 | 0.89 | PRKD3 (0.47) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7977742 | 0.88 | PRKD3 (0.49) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7978074 | 0.88 | DGAT1 (0.40) | MAPT | |
| SCHEMBL7991809 | 0.86 | SIRT2 (0.59) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7989667 | 0.85 | SIRT2 (0.61) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7977895 | 0.84 | SIRT2 (0.61) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7977730 | 0.84 | SIRT2 (0.50) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7991536 | 0.83 | SIRT2 (0.52) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7988148 | 0.83 | PRKD3 (0.45) | PRKD3MAP4K4PIM1CLK2MAP4K2 | |
| SCHEMBL7989731 | 0.83 | SIRT2 (0.49) | PRKD3MAP4K4PIM1CLK2MAP4K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |