Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.65 |
| ▸ | CNR2 | P34972 | 4/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | TSPO | P30536 | 2/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219356 | 0.83 | CNR1 (0.67) | CNR1CNR2MAPTMAPK1KDM4E | |
| SCHEMBL7963615 | 0.79 | CNR1 (1.00) | CNR1CNR2OPRK1HTR1ATSPO | |
| SCHEMBL14369638 | 0.77 | KDM4E (0.68) | MAPTMAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL219061 | 0.75 | KDM4E (0.69) | CNR1CNR2MAPTMAPK1KDM4E | |
| SCHEMBL4633677 | 0.75 | PDE4B (0.52) | CNR1ALDH1A1RECQLPOLBAPEX1 | |
| SCHEMBL4791922 | 0.75 | KDM4E (0.57) | CNR1CNR2MAPTMAPK1KDM4E | |
| SCHEMBL4074146 | 0.72 | KDM4E (0.65) | CNR1CNR2MAPTMAPK1KDM4E | |
| SCHEMBL19544901 | 0.72 | ALDH1A1 (0.52) | MAPTMAPK1ALDH1A1KDM4ERECQL | |
| SCHEMBL3825455 | 0.70 | CNR1 (0.59) | CNR1CNR2OPRK1HTR1ATSPO | |
| SCHEMBL7884933 | 0.70 | KDM4E (0.78) | MAPTMAPK1ALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140210-A2 | RADIOTRACERS FOR IMAGING CANNABINOID SUB-TYPE1 (CB1) RECEPTOR | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-11-19 | — | — | WO | disclosed |