SCHEMBL7977832

SCHEMBL7977832

CCCCCCCCCCOP(O)O.c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.43
PTPN11 Q06124 2/20 0.42
NR5A1 Q13285 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NR1I2 O75469 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
LTA4H P09960 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27623128 0.87 TSHR (0.45) TSHRLMNAALDH1A1CYP3A4TP53
Biphenyl SCHEMBL27870570 0.87 TSHR (0.45) TSHRLMNAALDH1A1CYP3A4TP53
Biphenyl SCHEMBL27870569 0.87 TSHR (0.45) TSHRLMNAALDH1A1CYP3A4TP53
Phenol SCHEMBL11358470 0.86 NR5A1 (0.51) TSHRLMNAALDH1A1CYP3A4TP53
Toluene SCHEMBL27561544 0.86 TSHR (0.44) TSHRLMNAALDH1A1CYP3A4TP53
Phenol SCHEMBL9046743 0.86 NR5A1 (0.51) TSHRLMNAALDH1A1CYP3A4TP53
SCHEMBL3319123 0.84 THRB (0.44) TSHRLMNAALDH1A1MEN1KMT2A
SCHEMBL3716811 0.84 THRB (0.44) TSHRLMNAALDH1A1MEN1KMT2A
SCHEMBL6267170 0.84 THRB (0.44) TSHRLMNAALDH1A1MEN1KMT2A
SCHEMBL22261008 0.84 THRB (0.44) TSHRLMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128819-C Water soluble polymers and their use in cosmetic formulations BASF AG (DE) 2003-11-26 CN disclosed
US-6271327-B1 HYDROXYALKYLACRYLIC AMIDES AND DIHYDROXYALKYLACRYLIC IMIDE POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed
US-6060566-A HYDROLYZED N-VINYL FORMAMIDE-CONTAINING GRAFT POLYMERS; PAPERMAKING; CARDBOARD; WET AND DRY STRENGTH AGENTS; PROMOTERS IN DIKETENE SIZING AND STARCH CATIONIZATION AGENTS; DISPERSANTS FOR PIGMENTS AND AS CREPING AIDES; TISSUE PAPER BASF AKTIENGESELLSCHAFT (DE) 2000-05-09 US disclosed
US-6048945-A MIXTURE OF VINYLCARBOXAMIDE WITH UNSATURATED MONOMER FOR GRAFT POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
CN-1232473-A Water-soluble polymers and their use in cosmetic formulations BASF AG (DE) 1999-10-20 CN disclosed
US-5578678-A N-VINYLCARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5543459-A MONO-, OLIGO- OR POLYSACCHARIDES GRAFTED TO A HYDROLYZED HOMO- OR COPOLYMER; WET OR DRY STRENGTH AGENTS ADDED TO PAPER STOCK PRIOR TO SHEET FORMATION BASF AKTIENGESELLSCHAFT (DE) 1996-08-06 US disclosed
US-5334287-A Improving dry and wet strength of paper BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed
US-5126395-A Catalytic emulsion polymerization of N-vinylamides, then acid or base hydrolysis, addition of antioxidants, reducing agents or aldehyde acceptors BASF AKTIENGESELLSCHAFT (DE) 1992-06-30 US disclosed