SCHEMBL797787

SCHEMBL797787

c1ccc2cc3cc4c(-c5ccc6cc7cc8ccc9cc%10ccccc%10cc9c8cc7cc6c5)cccc4cc3cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.48
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 5/20 0.46
HIF1A Q16665 4/20 0.46
CYP1B1 Q16678 1/20 0.46
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
ESR2 Q92731 2/20 0.43
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
HPGD P15428 3/20 0.40
CYP1A2 P05177 2/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
ESR1 P03372 1/20 0.39
MCL1 Q07820 1/20 0.39
ACMSD Q8TDX5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218724 0.98 GSTP1 (0.50) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL27707710 0.98 GSTP1 (0.50) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL27889944 0.96 GSTP1 (0.53) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL6691189 0.96 GSTP1 (0.53) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL28341419 0.96 GSTP1 (0.52) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL29451176 0.94 GSTP1 (0.55) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL1041948 0.94 GSTP1 (0.55) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
Anthracene SCHEMBL27770411 0.94 GSTP1 (0.55) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL11228390 0.90 GSTP1 (0.47) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL1527420 0.89 ALDH1A1 (0.59) GSTP1ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1262469-B1 POLYACENE DERIVATIVES AND PRODUCTION THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2012-01-11 EP disclosed