SCHEMBL7977893

SCHEMBL7977893

Cc1cc(O)cc(Cl)c1OCCCCNC(=O)c1ccc(C(F)(F)F)cn1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 10/20 0.45
PPARD Q03181 2/20 0.44
SCN10A Q9Y5Y9 2/20 0.42
GCGR P47871 3/20 0.41
MRGPRX4 Q96LA9 2/20 0.40
RHOC P08134 1/20 0.40
RHOA P61586 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977383 0.97 SCN9A (0.48) SCN9APPARDSCN10AGCGRMRGPRX4
SCHEMBL7977991 0.93 SCN9A (0.46) SCN9APPARDSCN10AMRGPRX4RHOC
SCHEMBL7975901 0.90 SCN9A (0.49) SCN9APPARDSCN10AMRGPRX4RHOC
SCHEMBL7979240 0.89 SCN9A (0.45) SCN9APPARDSCN10AGCGR
SCHEMBL7965796 0.88 RHOC (0.47) PPARDMRGPRX4RHOCRHOA
SCHEMBL7977459 0.86 SCN9A (0.47) SCN9APPARDSCN10AGCGRRHOC
SCHEMBL7965640 0.85 RHOC (0.51) PPARDMRGPRX4RHOCRHOA
SCHEMBL7979635 0.84 SCN9A (0.42) SCN9APPARDSCN10AGCGRRHOC
SCHEMBL7071524 0.83 GAA (0.42) PPARD
SCHEMBL7072961 0.81 MRGPRX4 (0.43) MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed