Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991996 | 0.93 | AURKA (0.56) | AURKAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL7989458 | 0.87 | LMNA (0.48) | AURKAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL7988160 | 0.84 | MEN1 (0.51) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL7991912 | 0.84 | MEN1 (0.51) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL7978042 | 0.83 | LMNA (0.58) | AURKAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL7990144 | 0.83 | MEN1 (0.53) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL7978170 | 0.82 | MEN1 (0.52) | KMT2AMEN1MAPTKDM4ENPC1 | |
| SCHEMBL7989738 | 0.82 | PARP1 (0.45) | AURKAKMT2AMAPTALDH1A1ABCB1 | |
| SCHEMBL7988225 | 0.81 | FGFR1 (0.54) | AURKAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL7988617 | 0.81 | MEN1 (0.51) | KMT2AMEN1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |