Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26978407 | 0.76 | KMT2A (0.44) | KMT2APIK3CDALDH1A1HSP90AA1MAPT | |
| SCHEMBL8866018 | 0.75 | HDAC8 (0.40) | KMT2APIK3CDHDAC8GRM4 | |
| SCHEMBL1556668 | 0.74 | KMT2A (0.39) | KMT2AALDH1A1IDO1TDO2NAMPT | |
| Hydrazine SCHEMBL28241715 | 0.74 | KMT2A (0.43) | KMT2APIK3CDALDH1A1PKMHDAC8 | |
| SCHEMBL27983255 | 0.71 | — | — | |
| SCHEMBL10715836 | 0.71 | — | — | |
| Formic Acid SCHEMBL28287308 | 0.71 | KMT2A (0.41) | KMT2APIK3CDALDH1A1HSP90AA1MAPT | |
| Water SCHEMBL23727754 | 0.70 | — | — | |
| SCHEMBL27926586 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28317604 | 0.70 | KMT2A (0.43) | KMT2APIK3CDALDH1A1MAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5112545-A | — | — | None | — | — | JP | disclosed |
| US-6277871-B1 | ANTICANCER AGENTS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| JP-H05112545-A | NEW ALPHA-METHYLENE-5-THIAZOLACETIC ACID DERIVATIVE, ITS PREPARATION AND INTERMEDIATE THEREOF, ITS USE AS DISINFECTANT AND COMPOSITION CONTAINING THE SAME | ROUSSEL UCLAF | 1993-05-07 | — | — | JP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |
| US-3844798-A | SPECTRALLY SENSITIZED LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL | AGFA GEVAERT AG | 1974-10-29 | — | — | US | disclosed |