SCHEMBL7977940

SCHEMBL7977940

O=C1COc2ccc(N3C(=O)C4=C(CCCC4)C3=O)nc2N1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 11/20 0.50
NR3C1 P04150 1/20 0.45
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30406609 0.76 NR3C2 (0.53) NR3C2NR3C1
SCHEMBL23871625 0.76 NR3C2 (0.53) NR3C2NR3C1
SCHEMBL7980616 0.73 NR3C2 (0.50) NR3C2NR3C1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL17695492 0.72 NR3C2 (0.57) NR3C2NR3C1
SCHEMBL1335047 0.70 NR3C2 (0.74) NR3C2NR3C1KMT2A
SCHEMBL9599303 0.70 NR3C2 (0.38) NR3C2NR3C1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL1335049 0.70 NR3C2 (0.74) NR3C2NR3C1KMT2A
SCHEMBL1334901 0.70 NR3C2 (0.74) NR3C2NR3C1KMT2A
SCHEMBL7977855 0.70 NR3C2 (0.49) NR3C2NR3C1
SCHEMBL592791 0.69 NR3C2 (0.47) NR3C2NR3C1ALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed