Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968012 | 0.74 | TP53 (0.42) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL4095480 | 0.73 | MMP12 (0.44) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL7954932 | 0.72 | ALDH1A1 (0.34) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15053068 | 0.71 | DRD2 (0.43) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8182873 | 0.70 | NR3C2 (0.42) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14080066 | 0.70 | MMP12 (0.49) | NR3C2KMT2ASMN1; SMN2HTR1AHTR1D | |
| SCHEMBL7977940 | 0.70 | NR3C2 (0.50) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL7966147 | 0.69 | MAPT (0.32) | NR3C2NPSR1 | |
| SCHEMBL24775925 | 0.67 | HTR1A (0.43) | NR3C2ALDH1A1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15052486 | 0.67 | MAPT (0.44) | NR3C2ALDH1A1HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5345781-A | — | — | None | — | — | JP | disclosed |
| JP-H05345781-A | BENZOXAZINE DERIVATIVE | SUMITOMO CHEM CO LTD | 1993-12-27 | — | — | JP | disclosed |