Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989181 | 0.95 | DPP4 (0.72) | DPP4PREP | |
| Trifluoroacetic Acid SCHEMBL7978160 | 0.88 | DPP4 (0.69) | DPP4DPP8PREP | |
| Trifluoroacetic Acid SCHEMBL7989205 | 0.87 | DPP4 (0.88) | DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL7978424 | 0.85 | DPP4 (0.65) | DPP4DPP8PREP | |
| Trifluoroacetic Acid SCHEMBL7992003 | 0.84 | DPP4 (0.62) | DPP4DPP8PREP | |
| SCHEMBL7989090 | 0.84 | DPP4 (0.76) | DPP4PREP | |
| SCHEMBL7977740 | 0.84 | DPP4 (0.76) | DPP4DPP8 | |
| SCHEMBL7989092 | 0.84 | DPP4 (0.76) | DPP4PREP | |
| SCHEMBL7992389 | 0.81 | DPP4 (0.78) | DPP4 | |
| SCHEMBL7989871 | 0.81 | DPP4 (0.75) | DPP4DPP8PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172081-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS; NON-INSULIN DEPENDENT DIABETES | NOVARTIS AG (CH) | 2001-01-09 | — | — | US | disclosed |