Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.88 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827030 | 0.94 | DPP4 (1.00) | DPP4DPP8FAPDPP9DPP7 | |
| SCHEMBL14392405 | 0.94 | DPP4 (1.00) | DPP4DPP8FAPDPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL7978160 | 0.89 | DPP4 (0.69) | DPP4DPP8FAPDPP9 | |
| SCHEMBL7977740 | 0.88 | DPP4 (0.76) | DPP4DPP8FAP | |
| Trifluoroacetic Acid SCHEMBL7977945 | 0.87 | DPP4 (0.66) | DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL7978424 | 0.86 | DPP4 (0.65) | DPP4DPP8FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL7992003 | 0.85 | DPP4 (0.62) | DPP4DPP8FAPDPP7 | |
| SCHEMBL7989092 | 0.83 | DPP4 (0.76) | DPP4 | |
| SCHEMBL7989090 | 0.83 | DPP4 (0.76) | DPP4 | |
| SCHEMBL7992389 | 0.82 | DPP4 (0.78) | DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172081-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS; NON-INSULIN DEPENDENT DIABETES | NOVARTIS AG (CH) | 2001-01-09 | — | — | US | disclosed |