SCHEMBL7977988

SCHEMBL7977988

O=c1ccn(N2C=CC=CC2)c(=O)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.39
DDB1 Q16531 1/20 0.36
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21183289 0.66 CRBN (0.45) CRBNDDB1PKM
SCHEMBL10423652 0.65
SCHEMBL28277546 0.65 CRBN (0.48) CRBNDDB1PKM
SCHEMBL27680064 0.65 KMT2A (0.46) CRBNDDB1PKM
SCHEMBL589950 0.63
SCHEMBL11623275 0.63 CRBN (0.42) CRBNDDB1PKM
SCHEMBL30940537 0.61
SCHEMBL29246519 0.60
Hydrochloric Acid SCHEMBL1071446 0.59
SCHEMBL7348642 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed