Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.30 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.30 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426470 | 0.80 | CRBN (0.58) | CRBNDDB1PKMALDH1A1L3MBTL1 | |
| SCHEMBL11623275 | 0.69 | CRBN (0.42) | CRBNDDB1PKMALDH1A1L3MBTL1 | |
| SCHEMBL6227943 | 0.68 | CRBN (0.41) | CRBNDDB1ALDH1A1LMNA | |
| SCHEMBL7977988 | 0.66 | CRBN (0.39) | CRBNDDB1PKM | |
| SCHEMBL9443401 | 0.64 | CRBN (0.41) | CRBNDDB1PKMSLC28A1SLC28A2 | |
| SCHEMBL23119506 | 0.64 | CRBN (0.50) | CRBNDDB1PKMALDH1A1L3MBTL1 | |
| SCHEMBL7157402 | 0.63 | CRBN (0.44) | CRBNDDB1PKMLMNADUT | |
| SCHEMBL5797252 | 0.63 | CRBN (0.41) | CRBNDDB1ALDH1A1L3MBTL1DUT | |
| SCHEMBL21385228 | 0.63 | — | — | |
| SCHEMBL710129 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3514164-B1 | NUCLEOSIDE DERIVATIVE OR SALT THEREOF, REAGENT FOR SYNTHESIZING POLYNUCLEOTIDE, METHOD FOR PRODUCING POLYNUCLEOTIDE, POLYNUCLEOTIDE, AND METHOD FOR PRODUCING BINDING NUCLEIC ACID MOLECULE | NEC SOLUTION INNOVATORS LTD (JP) | 2020-09-09 | — | — | EP | disclosed |
| EP-3546471-A1 | NUCLEOSIDE DERIVATIVE OR SALT THEREOF, POLYNUCLEOTIDE SYNTHESIS REAGENT, POLYNUCLEOTIDE PRODUCTION METHOD, POLYNUCLEOTIDE, AND BINDING NUCLEIC ACID MOLECULE PRODUCTION METHOD | NEC Solution Innovators, Ltd. (JP) | 2019-10-02 | — | — | EP | disclosed |
| EP-3514164-A1 | NUCLEOSIDE DERIVATIVE OR SALT THEREOF, REAGENT FOR SYNTHESIZING POLYNUCLEOTIDE, METHOD FOR PRODUCING POLYNUCLEOTIDE, POLYNUCLEOTIDE, AND METHOD FOR PRODUCING BINDING NUCLEIC ACID MOLECULE | NEC Solution Innovators, Ltd. (JP) | 2019-07-24 | — | — | EP | disclosed |