Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988978 | 0.80 | GBA1 (0.41) | CYSLTR1 | |
| Proxyfan SCHEMBL4072620 | 0.78 | HRH3 (0.54) | — | |
| SCHEMBL7974330 | 0.77 | CNR1 (0.41) | — | |
| SCHEMBL7510398 | 0.75 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL4846979 | 0.75 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL7960978 | 0.74 | HRH3 (0.47) | — | |
| SCHEMBL4846232 | 0.74 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL2353460 | 0.73 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| Proxyfan SCHEMBL15130144 | 0.73 | HRH3 (0.48) | — | |
| SCHEMBL4384967 | 0.72 | CYSLTR2 (0.33) | CYSLTR1CYSLTR2GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |