Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168121 | 0.89 | POLB (0.80) | POLBALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14899242 | 0.84 | ALDH1A1 (0.65) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19175628 | 0.82 | NPSR1 (0.65) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20064055 | 0.81 | KMT2A (0.62) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL30690828 | 0.81 | NPSR1 (0.64) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL27277527 | 0.81 | NPSR1 (0.64) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL279945 | 0.80 | NPSR1 (0.97) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL2493968 | 0.80 | ALDH1A1 (0.71) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL14924433 | 0.80 | SMN1; SMN2 (0.70) | NPSR1POLBALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10195008 | 0.79 | NPSR1 (0.94) | NPSR1POLBALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |
| EP-0971892-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042670-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-01 | — | — | WO | disclosed |