Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978399 | 1.00 | MEN1 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7766502 | 0.86 | MEN1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7771572 | 0.86 | MEN1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7834746 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL7821824 | 0.78 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL7822919 | 0.76 | POLB (0.36) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL7836651 | 0.76 | POLB (0.36) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL7822922 | 0.76 | POLB (0.36) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL7979984 | 0.76 | POLB (0.36) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL8477162 | 0.76 | CHRNA7 (0.40) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |