⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859372 | 0.67 | — | — | |
| SCHEMBL1286153 | 0.67 | — | — | |
| SCHEMBL2253865 | 0.67 | — | — | |
| SCHEMBL15597832 | 0.64 | ALDH1A1 (0.43) | — | |
| SCHEMBL6179885 | 0.63 | — | — | |
| SCHEMBL19090961 | 0.62 | TSHR (0.39) | — | |
| SCHEMBL15427287 | 0.62 | — | — | |
| SCHEMBL16924077 | 0.62 | — | — | |
| SCHEMBL18536609 | 0.62 | — | — | |
| SCHEMBL1363461 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137469-A1 | NOVEL CLASS OF COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2017-08-17 | — | — | WO | disclosed |
| EP-3046156-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-6214842-B1 | TREATING METABOLIC DISORDERS RELATED TO INSULIN RESISTANCE OR HYPERGLYCEMIA TYPICALLY ASSOCIATED WITH OBESITY OR GLUCOSE INTOLERANCE; TREATING DIABETES TYPES I AND II | WYETH | 2001-04-10 | — | — | US | disclosed |