Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833145 | 0.87 | SIGMAR1 (0.66) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL19944762 | 0.83 | SIGMAR1 (0.64) | SIGMAR1MAPK1MEN1KMT2ADRD2 | |
| SCHEMBL14067029 | 0.83 | MAPK1 (0.46) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL8010714 | 0.83 | SIGMAR1 (0.72) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7910148 | 0.83 | NPSR1 (0.60) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL27914131 | 0.82 | SIGMAR1 (0.57) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL8508337 | 0.82 | CYP2D6 (0.58) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL11835654 | 0.80 | SIGMAR1 (0.62) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL19944415 | 0.80 | SIGMAR1 (0.62) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL11833132 | 0.79 | SIGMAR1 (0.60) | SIGMAR1MAPK1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326496-B1 | REDUCTION WITH METAL HYDRIDE | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-12-04 | — | — | US | disclosed |