Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | RHOA | P61586 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RHOC | P08134 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554906 | 0.83 | RAB9A (0.72) | RAB9APOLBALDH1A1PTPN1KMT2A | |
| SCHEMBL26986504 | 0.83 | TP53 (0.57) | RAB9ARHOAPOLBALDH1A1PTPN1 | |
| SCHEMBL27136774 | 0.83 | RAB9A (0.55) | RAB9ARHOAPOLBALDH1A1GAA | |
| SCHEMBL27124630 | 0.83 | TP53 (0.57) | RAB9ARHOAPOLBALDH1A1PTPN1 | |
| SCHEMBL5554898 | 0.83 | RAB9A (0.72) | RAB9APOLBALDH1A1PTPN1KMT2A | |
| SCHEMBL26986347 | 0.83 | RAB9A (0.55) | RAB9ARHOAPOLBALDH1A1GAA | |
| SCHEMBL23130434 | 0.82 | PTPN1 (0.68) | RAB9AALDH1A1EPHX1PAX8PTPN1 | |
| SCHEMBL29136093 | 0.80 | DPP4 (0.48) | EPHX1KMT2ACCR2 | |
| SCHEMBL27177281 | 0.80 | DPP4 (0.48) | EPHX1KMT2ACCR2 | |
| SCHEMBL23390168 | 0.77 | EPHX2 (0.60) | RAB9ARHOAPOLBALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268380-B1 | E.G., ETHYL BETA-((N-3(((4(AMINOIMINOMETHYL)PHENYL)AMINO)CARBONYL)PIPERIDY LCARBONYL)AMINO)-3-PYRIDINEPROPANOATE | G. D. SEARLE & CO. | 2001-07-31 | — | — | US | disclosed |
| WO-1994019341-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-01 | — | — | WO | disclosed |