Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766169 | 0.85 | CRHR1 (0.39) | CRHR1MAPTLMNAKDM4EPKM | |
| SCHEMBL14388994 | 0.78 | CRHR1 (0.40) | CRHR1RAPGEF4MAPTL3MBTL1LMNA | |
| SCHEMBL7978901 | 0.75 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL14388961 | 0.73 | NQO2 (0.33) | — | |
| SCHEMBL5788960 | 0.73 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL5787141 | 0.73 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL6025654 | 0.71 | CRHR1 (0.61) | CRHR1MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL28704856 | 0.69 | EIF4EBP1 (0.41) | — | |
| SCHEMBL14388998 | 0.69 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL3902018 | 0.68 | CRHR1 (0.34) | CRHR1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211195-B1 | NERVOUS SYSTEM, PSYCHOLOGICAL AND GLANDULAR DISORDERS | NEUROCRINE BIOSCIENCES, INC. | 2001-04-03 | — | — | US | disclosed |