Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426885 | 1.00 | MEN1 (0.32) | MEN1KMT2AFFAR1GPR84PNP | |
| SCHEMBL1348160 | 0.92 | KMT2A (0.41) | MEN1KMT2AFFAR1GPR84PNP | |
| SCHEMBL1347205 | 0.90 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL1350244 | 0.89 | MPO (0.33) | FFAR1GPR84 | |
| SCHEMBL1349154 | 0.87 | MGAM (0.34) | FFAR1GPR84 | |
| SCHEMBL1349559 | 0.85 | MEN1 (0.33) | MEN1KMT2APNP | |
| SCHEMBL1349184 | 0.84 | MEN1 (0.34) | MEN1KMT2AFFAR1GPR84PNP | |
| SCHEMBL1349318 | 0.83 | MEN1 (0.32) | MEN1KMT2AFFAR1GPR84PNP | |
| SCHEMBL1350623 | 0.83 | PNP (0.33) | MEN1KMT2APNP | |
| SCHEMBL1348363 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156072-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-30 | — | — | WO | disclosed |