Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.68 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7979082 | 0.96 | ITGAV (0.64) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| Trifluoroacetic Acid SCHEMBL7979079 | 0.96 | ITGAV (0.64) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7982200 | 0.95 | ITGAV (0.61) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7969186 | 0.90 | ITGAV (0.55) | ITGAVITGB3ITGA2B | |
| SCHEMBL7979084 | 0.89 | ITGAV (0.55) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7980652 | 0.89 | ITGB3 (0.61) | ITGAVITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7982829 | 0.87 | ITGB3 (0.61) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| Trifluoroacetic Acid SCHEMBL7982837 | 0.87 | ITGB3 (0.61) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7980623 | 0.87 | ITGB3 (0.69) | ITGAVITGB3ITGA2B | |
| SCHEMBL7979281 | 0.86 | ITGAV (0.59) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |