Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.51 |
| ▸ | ITGAV | P06756 | 17/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982238 | 0.90 | ITGAV (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL7982175 | 0.89 | ITGAV (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL7979281 | 0.88 | ITGAV (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969370 | 0.88 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969228 | 0.86 | ITGB3 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL7980652 | 0.85 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969236 | 0.83 | ITGB3 (0.39) | ITGB3ITGAVITGA2BMMP2MMP9 | |
| SCHEMBL7985750 | 0.80 | ITGB3 (0.37) | ITGB3ITGAVITGA2BMMP2MMP9 | |
| SCHEMBL7985747 | 0.80 | ITGB3 (0.37) | ITGB3ITGAVITGA2BMMP2MMP9 | |
| SCHEMBL7356042 | 0.80 | ITGB3 (0.54) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |