Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | RHOC | P08134 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976020 | 0.97 | TRPV1 (0.52) | TRPV1HDAC3HDAC1HDAC2CYP3A4 | |
| SCHEMBL7979069 | 0.93 | TRPV1 (0.57) | TRPV1HDAC3HDAC1HDAC2RHOC | |
| SCHEMBL7979022 | 0.89 | TRPV1 (0.56) | TRPV1HDAC3HDAC1HDAC2RHOC | |
| SCHEMBL7965640 | 0.89 | RHOC (0.51) | TRPV1RHOCRHOAEPHX2NPC1 | |
| SCHEMBL7981831 | 0.88 | HDAC3 (0.49) | TRPV1HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL7981926 | 0.86 | NPC1 (0.54) | HDAC3HDAC1HDAC2RHOCRHOA | |
| SCHEMBL7965796 | 0.85 | RHOC (0.47) | RHOCRHOAEPHX2PPARD | |
| SCHEMBL7977604 | 0.85 | EPHX2 (0.50) | TRPV1HDAC3HDAC1HDAC2MCHR1 | |
| SCHEMBL7965774 | 0.84 | NPC1 (0.49) | NPC1 | |
| SCHEMBL7979257 | 0.83 | NPC1 (0.50) | HDAC3HDAC1HDAC2RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |
| CN-1187809-A | Dihalopropene compound, insecticide containing the same as active ingredient, and production intermediate thereof | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | CN | disclosed |