Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | JAK1 | P23458 | 5/20 | 0.42 |
| ▸ | TYK2 | P29597 | 5/20 | 0.42 |
| ▸ | JAK3 | P52333 | 5/20 | 0.42 |
| ▸ | CDK4 | P11802 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982406 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL10139785 | 0.82 | CNR1 (0.55) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL10139787 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL7975946 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL15788683 | 0.80 | NPC1 (0.57) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL7973109 | 0.79 | F10 (0.52) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL7973887 | 0.79 | F10 (0.70) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL10139800 | 0.79 | CHEK1 (0.56) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL10139794 | 0.78 | F9 (0.56) | KDM4EALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL7975272 | 0.77 | ITK (0.63) | KDM4EALDH1A1HTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |