Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.70 |
| ▸ | F9 | P00740 | 4/20 | 0.70 |
| ▸ | F7 | P08709 | 4/20 | 0.70 |
| ▸ | F11 | P03951 | 3/20 | 0.70 |
| ▸ | PLAU | P00749 | 7/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.55 |
| ▸ | F2 | P00734 | 9/20 | 0.53 |
| ▸ | PLG | P00747 | 6/20 | 0.53 |
| ▸ | PLAT | P00750 | 6/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10139800 | 0.89 | CHEK1 (0.56) | F10F9F7F11KDM4E | |
| SCHEMBL7973776 | 0.82 | F10 (1.00) | F10F9F7F11PLAU | |
| SCHEMBL14599542 | 0.82 | PLAU (0.79) | F10F9F7F11PLAU | |
| SCHEMBL7982406 | 0.81 | KDM4E (0.50) | F10F9F7F11KDM4E | |
| SCHEMBL9607771 | 0.81 | F10 (0.83) | F10F9F7F11PLAU | |
| SCHEMBL7975946 | 0.81 | KDM4E (0.68) | F10F9F7F11KDM4E | |
| SCHEMBL7960699 | 0.81 | F10 (0.67) | F10F9F7F11PLAU | |
| SCHEMBL7969187 | 0.81 | F10 (0.67) | F10F9F7F11PLAU | |
| SCHEMBL20307774 | 0.81 | F10 (0.67) | F10F9F7F11PLAU | |
| SCHEMBL7979283 | 0.79 | KDM4E (0.47) | F10F9F7F11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-2805939-A1 | Heterocyclic compounds as factor IXA inhibitors. | Merck Sharp & Dohme Corp. (US) | 2014-11-26 | — | — | EP | disclosed |
| US-20130157281-A1 | Factor IXa Crystals, Related Complexes and Methods | SCHERING CORPORATION (US) | 2013-06-20 | — | — | US | disclosed |
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-7968683-B1 | Factor IXa crystals, related complexes and methods | SCHERING CORPORATION (US) | 2011-06-28 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | F9, F12, F8 | F10 11/4885F9 1/4885F7 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.