SCHEMBL7979378

SCHEMBL7979378

CCc1cc(OCC=C(Cl)Cl)cc(C)c1OCCCNCc1ccc(C(F)(F)F)cn1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 6/20 0.39
PPARD Q03181 4/20 0.34
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
FAAH O00519 1/20 0.32
GAA P10253 1/20 0.32
SCN9A Q15858 1/20 0.31
FGFR4 P22455 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM1A O60341 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7965836 0.97 SCN8A (0.37) SCN8APPARDPPARGPPARAPOLB
SCHEMBL7977744 0.95 SCN8A (0.37) SCN8APPARGPOLBFAAHGAA
SCHEMBL7979520 0.93 SCN8A (0.45) SCN8APPARDPPARGPPARAPOLB
SCHEMBL7979536 0.92 KDM4E (0.35) SCN8APPARGPOLBFAAHGAA
SCHEMBL7979403 0.90 SCN8A (0.42) SCN8APPARDPPARGPPARAGAA
SCHEMBL7977978 0.90 SCN8A (0.40) SCN8APPARDPPARGPPARAPOLB
SCHEMBL7979631 0.87 SCN8A (0.38) SCN8APPARDPPARGPPARAMEN1
SCHEMBL7079367 0.86 POLB (0.38) SCN8APPARDPPARGPPARAPOLB
SCHEMBL7979291 0.85 SCN8A (0.37) SCN8APOLBMEN1KMT2AALDH1A1
SCHEMBL7982189 0.85 SCN8A (0.37) SCN8APPARDPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed