SCHEMBL7979536

SCHEMBL7979536

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCNCc1ccc(C(F)(F)F)cn1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
P4HB P07237 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SCN8A Q9UQD0 3/20 0.35
FAAH O00519 1/20 0.34
KDM1A O60341 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PPARG P37231 3/20 0.32
HTT P42858 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
SLC2A1 P11166 1/20 0.31
DAO P14920 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDE2A O00408 1/20 0.31
SCN9A Q15858 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977744 0.97 SCN8A (0.37) KDM4EP4HBNPSR1SCN8AFAAH
SCHEMBL7965836 0.95 SCN8A (0.37) KDM4EP4HBNPSR1SCN8AFAAH
SCHEMBL7979378 0.92 SCN8A (0.39) SCN8AFAAHKDM1AMAOAMAOB
SCHEMBL7979403 0.89 SCN8A (0.42) KDM4ESCN8AKDM1AMAOAMAOB
SCHEMBL7976161 0.88 SCN8A (0.34) KDM4ESCN8AKDM1AMAOAMAOB
SCHEMBL7976373 0.88 SCN8A (0.34) SCN8AKDM1AMAOAMAOBALDH1A1
SCHEMBL7979520 0.86 SCN8A (0.45) SCN8AKDM1AMAOAMAOBPPARG
SCHEMBL7979631 0.86 SCN8A (0.38) KDM4ESCN8AKDM1AMAOAMAOB
SCHEMBL7073219 0.85 PRKAB2 (0.39) KDM4EPPARGHTTPOLBGAA
SCHEMBL7979291 0.85 SCN8A (0.37) KDM4ESCN8AKDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed