SCHEMBL7979386

SCHEMBL7979386

O=C(NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc2ccccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
ALDH1A1 P00352 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
ATM Q13315 1/20 0.55
HPGD P15428 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SLC6A4 P31645 4/20 0.47
OPRM1 P35372 2/20 0.45
TMEM97 Q5BJF2 2/20 0.45
SIGMAR1 Q99720 2/20 0.45
OPRK1 P41145 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SLC6A2 P23975 1/20 0.44
PKM P14618 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979802 0.85 DRD2 (0.47) MAPTL3MBTL1
SCHEMBL7979368 0.85 MAPT (0.62) MAPTL3MBTL1ALDH1A1SMN1; SMN2ATM
SCHEMBL8075519 0.83 NPC1 (0.49) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL8082182 0.82 DRD2 (0.49)
SCHEMBL8067282 0.82 NPC1 (0.55) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7979053 0.82 MAPT (0.58) MAPTL3MBTL1ALDH1A1SMN1; SMN2ATM
SCHEMBL8060900 0.81 HPGD (0.40) ALDH1A1HPGDNPC1RAB9AMEN1
SCHEMBL7965974 0.80 SCN9A (0.46)
SCHEMBL7965955 0.79 KMT2A (0.51) ATMMEN1KMT2AKDM4ECYP1A2
SCHEMBL27559609 0.79 MAPT (0.69) MAPTL3MBTL1ALDH1A1SMN1; SMN2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed