SCHEMBL7979458

SCHEMBL7979458

CNC(=O)C(Cc1ccccc1)N(C)C(=O)[C@@H](Cc1cccc2ccccc12)N(C)C(=O)/C=C/CC(C)(C)N

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 8/20 0.49
HRH4 Q9H3N8 1/20 0.37
METAP2 P50579 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6318847 1.00 GHSR (0.49) GHSRHRH4METAP2MMP9
SCHEMBL6318213 1.00 GHSR (0.49) GHSRHRH4METAP2MMP9
SCHEMBL6319716 1.00 GHSR (0.49) GHSRHRH4METAP2MMP9
SCHEMBL6320106 1.00 GHSR (0.49) GHSRHRH4METAP2MMP9
SCHEMBL6316681 0.92 GHSR (0.49) GHSRMMP9
SCHEMBL6325138 0.92 GHSR (0.49) GHSRMMP9
SCHEMBL6316698 0.92 GHSR (0.49) GHSRMMP9
SCHEMBL6325135 0.92 GHSR (0.49) GHSRMMP9
SCHEMBL6320802 0.92 GHSR (0.59) GHSRMMP9
SCHEMBL6323451 0.92 GHSR (0.59) GHSRMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281247-B1 GLANDULAR DISORDERS; ANIMAL GROWTH REGULATORS NOVO NORDISK A/S (DK) 2001-08-28 US disclosed