Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967399 | 0.82 | RAB9A (0.40) | RAB9AKMT2ALMNANPC1NAMPT | |
| SCHEMBL4112906 | 0.72 | MAPT (0.64) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL10576308 | 0.71 | MAPT (0.86) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL8220313 | 0.71 | POLB (0.45) | MAPTRAB9AKMT2ALMNANAMPT | |
| SCHEMBL11617207 | 0.71 | MAPT (0.63) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL7976377 | 0.71 | HTT (0.56) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL4113073 | 0.71 | MAPT (0.71) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL4105709 | 0.70 | MAPT (0.73) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL4113552 | 0.70 | MAPT (0.68) | MAPTRAB9AKMT2ALMNANPC1 | |
| SCHEMBL15575212 | 0.69 | NAMPT (0.75) | MAPTRAB9AKMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |