Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979483 | 0.84 | CYP2C9 (0.41) | HDAC1HDAC6CYP2C9CYP2C19LMNA | |
| SCHEMBL1336193 | 0.76 | CYP2C9 (0.48) | HDAC1HDAC6CYP2C9CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL1335634 | 0.75 | CYP2C9 (0.47) | HDAC1HDAC6CYP2C9CYP2C19LMNA | |
| SCHEMBL10002584 | 0.72 | NTRK2 (0.40) | NTRK2 | |
| SCHEMBL4207867 | 0.70 | HDAC1 (0.57) | HDAC1HDAC6LMNATSHRMEN1 | |
| SCHEMBL2187701 | 0.70 | PDK1 (0.46) | HDAC1HDAC6CYP2C9CYP2C19LMNA | |
| SCHEMBL279761 | 0.68 | HRH1 (0.56) | CYP2C9CYP2C19CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL29833901 | 0.68 | USP2 (0.48) | HDAC1HDAC6CYP2C9CYP2C19LMNA | |
| SCHEMBL2755872 | 0.67 | USP2 (0.60) | CYP2C9CYP2C19LMNATSHRCYP1A2 | |
| SCHEMBL2187957 | 0.67 | PDK1 (0.44) | HDAC1HDAC6CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |