Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977403 | 0.86 | KDM4E (0.50) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL18239527 | 0.79 | HDAC4 (0.65) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL17401233 | 0.79 | HDAC6 (0.65) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL16011573 | 0.79 | HDAC4 (0.65) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL12124277 | 0.79 | KMT2A (0.69) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL17629364 | 0.79 | KDM4E (0.53) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL14421254 | 0.78 | HDAC8 (0.52) | HDAC4HDAC1HDAC6GAANPSR1 | |
| SCHEMBL12313374 | 0.78 | RAB9A (0.63) | HDAC4HDAC1HDAC6POLBKMT2A | |
| SCHEMBL14627824 | 0.78 | MAPK1 (0.64) | HDAC4HDAC1HDAC6KMT2ATDP1 | |
| SCHEMBL16315254 | 0.78 | GAA (0.69) | HDAC4HDAC1HDAC6POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |