Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | PLG | P00747 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 13/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 3/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.39 |
| ▸ | MARK3 | P27448 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026495 | 0.90 | ACSL1 (0.42) | F2ITKCHEK2PRKCGCSNK1D | |
| Hydrochloric Acid SCHEMBL7977856 | 0.87 | F2 (0.55) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8028962 | 0.77 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7968431 | 0.77 | F2 (0.59) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7979862 | 0.77 | F2 (0.65) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8029667 | 0.76 | ITK (0.43) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8029894 | 0.74 | ITK (0.43) | F2ITKCHEK2PRKCGCSNK1D | |
| SCHEMBL7968268 | 0.74 | F2 (0.45) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8027050 | 0.74 | ITK (0.45) | F2ITKCHEK2PRKCGCSNK1D | |
| Hydrochloric Acid SCHEMBL7427712 | 0.73 | F2 (0.58) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |