Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.45 |
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | PLG | P00747 | 7/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | USP14 | P54578 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985021 | 0.90 | CNR2 (0.43) | USP14BCHECNR2CNR1ITK | |
| SCHEMBL7967843 | 0.88 | F2 (0.43) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7968183 | 0.87 | F2 (0.60) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7977966 | 0.84 | CNR2 (0.40) | USP14BCHECNR2CNR1MEN1 | |
| SCHEMBL8029667 | 0.82 | ITK (0.43) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7967842 | 0.78 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7428352 | 0.76 | F2 (0.64) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7984703 | 0.74 | F2 (0.64) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7977875 | 0.74 | CNR2 (0.46) | F2F10PLGBCHECNR2 | |
| SCHEMBL7979533 | 0.74 | F2 (0.41) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |