Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30046476 | 0.84 | HTR2C (0.40) | ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL19363865 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GRIN2BCARM1PRMT6 | |
| SCHEMBL19363864 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GRIN2BCARM1PRMT6 | |
| SCHEMBL23633954 | 0.79 | SPHK1 (0.55) | ALDH1A1SMN1; SMN2GRIN2BCARM1PRMT6 | |
| SCHEMBL5689642 | 0.78 | GRIN2B (0.65) | GRIN2BSIGMAR1SPHK1 | |
| SCHEMBL5689574 | 0.78 | GRIN2B (0.65) | GRIN2BSIGMAR1SPHK1 | |
| SCHEMBL22433045 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2GRIN2BMPOSMYD3 | |
| SCHEMBL5689576 | 0.78 | GRIN2B (0.65) | GRIN2BSIGMAR1SPHK1 | |
| SCHEMBL17546369 | 0.78 | GRIN2B (0.51) | ALDH1A1SMN1; SMN2GRIN2BCARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL8009516 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2SMYD3SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228861-B1 | BENIGN PROSTATIC HYPERPLASIA; ANTICHOLESTEROL AGENTS; IMPOTENCY; INTRAOCULAR PRESSURE; ANTIARRHYTHMIA AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-08 | — | — | US | disclosed |