Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46511 | 0.96 | HPGD (0.58) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| Hydrochloric Acid SCHEMBL11543252 | 0.94 | HPGD (0.56) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| Hydrochloric Acid SCHEMBL2493592 | 0.94 | HPGD (0.56) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL10143861 | 0.90 | KEAP1 (0.52) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL7103505 | 0.88 | PAOX (0.53) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL21309925 | 0.87 | CARM1 (0.53) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL39802 | 0.83 | CARM1 (0.62) | SMN1; SMN2KEAP1HPGDDUSP3KDM4E | |
| SCHEMBL13867476 | 0.82 | PAOX (0.55) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL23471433 | 0.80 | EPHX2 (0.49) | SMN1; SMN2KEAP1HPGDDUSP3LMNA | |
| SCHEMBL8403611 | 0.80 | CARM1 (0.56) | SMN1; SMN2HPGDDUSP3MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |