SCHEMBL13468539

SCHEMBL13468539

COC(=O)C1CCCN1C(=O)c1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
ALOX5 P09917 2/20 0.53
ITGB3 P05106 1/20 0.52
ITGB1 P05556 1/20 0.52
ITGAV P06756 1/20 0.52
ITGA5 P08648 1/20 0.52
ITGA4 P13612 1/20 0.52
HTT P42858 1/20 0.50
PDK2 Q15119 1/20 0.50
TP53 P04637 1/20 0.49
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.46
ACE P12821 1/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
LOX P28300 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20366927 0.96 TP53 (0.54) CNR1CNR2ALOX5ITGB3ITGB1
SCHEMBL10724171 0.89 CNR1 (0.53) CNR1CNR2ALOX5PDK2KMT2A
SCHEMBL18314632 0.89 GAA (0.50) CNR1CNR2ALOX5PDK2GAA
SCHEMBL31562993 0.88 CNR1 (0.53) CNR1CNR2ALOX5PDK2NPC1
SCHEMBL12979193 0.88 CNR1 (0.53) CNR1CNR2ALOX5PDK2NPC1
SCHEMBL20366865 0.86 ALDH1A1 (0.56) ITGB3ITGB1ITGAVITGA5ITGA4
SCHEMBL13469109 0.85 CNR2 (0.53) CNR1CNR2ALOX5PDK2ALDH1A1
SCHEMBL15614468 0.85 CNR2 (0.51) CNR1CNR2ALOX5PDK2KMT2A
SCHEMBL8633268 0.84 CNR1 (0.50) CNR1CNR2ALOX5PDK2GAA
SCHEMBL20858858 0.84 ITGB1 (0.67) ITGB3ITGB1ITGAVITGA5ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169662-B1 SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2018-07-11 EP disclosed
EP-2510786-A1 Substituted Prop-2-in-1-ol and Prop-2-en-1-ol derivatives Bayer CropScience AG (DE) 2012-10-17 EP disclosed