Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979905 | 1.00 | NAPRT (0.48) | NAPRTLMNAECE1POLBHPGD | |
| SCHEMBL7966197 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7978664 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7976881 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7977066 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7976863 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7980129 | 0.89 | PTAFR (0.42) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7978383 | 0.89 | LMNA (0.46) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7976785 | 0.89 | ECE1 (0.48) | LMNAECE1POLBHPGDHTT | |
| SCHEMBL7978380 | 0.89 | LMNA (0.46) | LMNAECE1POLBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |